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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395423Generated: October 29, 2026

4-Piperidinecarboxamide → 1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]piperidine-4-carboxamide

https://huagongshe.com/reaction/395423

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidinecarboxamideHCID 3772—
Reactant4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
Product1-[[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl]piperidine-4-carboxamideHCID 22557982—

Reaction Steps

Piperidine-4-carboxamide (385 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (881 mg) were condensed by the same method as described in Example 2 to give the title compound as white needles.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605620B1
Source datasetuspto-grants-2003_08
ORD IDord-5379627ac29847d6b6dd54438147ef89
Source noteuspto-grants-2003_08