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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395429Generated: October 30, 2026

Piperonylamine → [2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidone

https://huagongshe.com/reaction/395429

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperonylamineHCID 2723901—
Reactant4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
Product[2-(3,4,5-Trimethoxyphenyl)pyridin-4-yl]methyl-4-piperidoneHCID 22557811—

Reaction Steps

4-Piperidone hydrochloride monohydrate (3.07 g) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (2.94 g) were coupled by the same manner as described in Example 2 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605620B1
Source datasetuspto-grants-2003_08
ORD IDord-5c82a2d9956947a48333765e37336b52
Source noteuspto-grants-2003_08