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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395444Generated: November 3, 2026

Ethyl 5-bromopyridine-3-carboxylate → Ethyl 5-(3,4,5-trimethoxyphenyl)nicotinate

https://huagongshe.com/reaction/395444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-bromopyridine-3-carboxylateHCID 140785—
Reactant3,4,5-Trimethoxybenzeneboronic acidHCID 2734390—
ProductEthyl 5-(3,4,5-trimethoxyphenyl)nicotinateHCID 22557861—

Reaction Steps

3,4,5-Trimethoxyphenylboronic acid (6.36 g) and ethyl 5-bromonicotinate (6.90 g) were reacted in the same manner as described in Preparation Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605620B1
Source datasetuspto-grants-2003_08
ORD IDord-ed23711a5ad2474b9c67044e4d9050f5
Source noteuspto-grants-2003_08