HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine → 1-(tert-butoxycarbonyl)-4-[N-(2-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine | HCID 22557874 | — |
| Reactant | tert-Butyl 4-((2-methoxyphenyl)amino)piperidine-1-carboxylate | HCID 22557919 | — |
| Product | 1-(tert-butoxycarbonyl)-4-[N-(2-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine | HCID 22557912 | — |
Reaction Steps
4-(o-Anisidino)-1-(tert-butoxycarbonyl)piperidine (613 mg) and 5-chloromethyl-3-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06605620B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-87739315a062476cbe51429bd6e0a245 |
| Source note | uspto-grants-2003_08 |