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4-(Trifluoromethyl)aniline → 1-Boc-4-(4-Trifluoromethyl-phenylamino)-piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| 反応物 | tert-Butyl 4-oxopiperidine-1-carboxylate | HCID 735900 | — |
| 生成物 | 1-Boc-4-(4-Trifluoromethyl-phenylamino)-piperidine | HCID 22029142 | — |
反応手順
1-(tert-Butoxycarbonyl)-4-piperidone (5.00 g) and 4-(trifluoromethyl)aniline (3.85 g) was treated in the same manner as described in Preparation Example 37 to give white powder of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06605620B1 |
| 出典データセット | uspto-grants-2003_08 |
| ORD ID | ord-1420590f7cb24c4fb388c04d73723f4b |
| 出典メモ | uspto-grants-2003_08 |