HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395573Generated: October 29, 2026
Bromine → 3-(Bromoacetyl)-4-hydroxybenzoic acid
https://huagongshe.com/reaction/395573
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 3-Acetyl-4-hydroxybenzoic acid | HCID 9179245 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(Bromoacetyl)-4-hydroxybenzoic acid | HCID 13573514 | — |
Reaction Steps
The compound obtained in Step A (32.2 mmol) is dissolved in glacial acetic acid (40 ml) and then 48.3 mmol of bromine are added. The mixture is heated at 80° C. for 2 hours and is then hydrolysed using ice-cold water. The precipitate obtained is filtered off, washed with water until a pH of 5-6 is obtained, and then dried and recrystallised.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06605632B1 |
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| Source dataset | uspto-grants-2003_08 |
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| ORD ID | ord-c386defd6d5e4fea945844a689b518b5 |
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| Source note | uspto-grants-2003_08 |
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