p-Anisoyl chloride → HCID 10644730, compound

HRID 395778Notes

Reaction equation

HRID 395778 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([C:11]#[N:12])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.[C:13](Cl)(=[O:22])[C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1>>[C:11]([C:9]1[CH:10]=[C:4]([NH:1][C:13](=[O:22])[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[C:5]([NH:6][C:13](=[O:22])[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[CH:7][CH:8]=1)#[N:12]

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 5959014-Amino-3-nitrobenzonitrile

Product 1

HCID 10644730HCID 10644730, compound

Procedure

Using the procedures described in Example 93, Part A and Example 96, Part B, 2-nitro-4-cyanoaniline (31 mmol) and 4-anisoyl chloride yielded 500 mg (21%, three steps) of the title compound.

Sources & evidence

ORD record
ord-94bf762db91f403c91f51b8ab226965b
Source dataset
uspto-grants-2003_08
Patent number
US06605626B2

Reaction notes

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