Aniline → 2-Nitro-N-Phenylbenzamide

HRID 395824Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:8]([C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13](Cl)=[O:14])([O-:10])=[O:9]>>[N+:8]([C:11]1[CH:19]=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:14])([O-:10])=[O:9]

Participants

Reactant 2

HCID 6115Aniline

HCID 118752-Nitrobenzoyl chloride

Product 1

HCID 7200512-Nitro-N-PhenylbenzamideYield 80.3%

Procedure

Using the procedure described in Example 93, Part A, aniline (11 mmol) and 2-nitrobenzoyl chloride (12.1 mmol) yielded 2.14 g (80%) of the title compound.

Sources & evidence

ORD record: ord-c5691cb19c8e4c0890c1ef51ae037f51
Source dataset: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06605626B2

Reaction notes

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