HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-[[(1-Methylpyridinium-4-yl)carbonyl]amino]-N-(4-chlorophenyl)benzamide Iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-{2-[(4-chloroanilino)carbonyl]phenyl}isonicotinamide | HCID 1099265 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-[[(1-Methylpyridinium-4-yl)carbonyl]amino]-N-(4-chlorophenyl)benzamide Iodide | HCID 69359238 | 59.3% |
Reaction Steps
To a stirring solution of 2-(4-pyridinecarbonyl)amino-N-(4-chlorophenyl)benzamide (500 mg, 1.42 mmol) in DMF (10 mL) was added methyl iodide (3 mL, 48 mmol). After 48 h, the precipitate was filtered, washed with diethyl ether and dried in vacuo to give 416 mg (59%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06605626B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-188efcd3d6c540ccaefca51e88697662 |
| Source note | uspto-grants-2003_08 |