Sodium borohydride → HCID 18173091, compound

HRID 395872Notes

Reaction equation

HRID 395872 reaction equation
[O:1]=[C:2]1[CH2:7][CH:6]2[CH:8]([C:9]3[NH:17][C:16]4[C:15](=[O:18])[N:14]([CH2:19][CH2:20][CH3:21])[C:13](=[O:22])[N:12]([CH2:23][CH2:24][CH3:25])[C:11]=4[N:10]=3)[CH:3]1[CH2:4][CH2:5]2.[BH4-].[Na+]>CO>[OH:1][CH:2]1[CH2:7][CH:6]2[CH:8]([C:9]3[NH:17][C:16]4[C:15](=[O:18])[N:14]([CH2:19][CH2:20][CH3:21])[C:13](=[O:22])[N:12]([CH2:23][CH2:24][CH3:25])[C:11]=4[N:10]=3)[CH:3]1[CH2:4][CH2:5]2

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 18173116HCID 18173116, compound

Product 1

HCID 18173091HCID 18173091, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

8-(2-Oxo-bicyclo[2.2.1]hept-7-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (200 mg) was reduced using NaBH4 (44 mg) in MeOH (10 ml). Yield 120 mg. Mass (ES+ 347).

Sources & evidence

ORD record
ord-7090a9025ce7441da54bef1aaa80503c
Source dataset
uspto-grants-2003_08
Patent number
US06605600B1

Reaction notes

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