HCID 10109179, compound → HCID 9946871, compound

Participants

Reaction Steps

8-(4-Hydroxy-bicyclo[3.2.1]oct-6-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (140 mg) from step 1 was taken in CH2Cl2 (5 ml). Celite (2 g) was added, followed by PCC (90 mg) and stirred at room temperature for 1 hr. Additional PCC (90 mg) was added and stirred for 2 hrs at room temperature. The reaction mixture was diluted with ether (100 ml) and filtered through celite and concentrated. Purified on silica column eluted with ethyl acetate:hexane (25:75) to yield 65 mg of the desired product. Mass (ES+ 369).

Provenance & Evidence