HCID 9946871, compound → HCID 18173055, compound

Participants

Reaction Steps

8-(4-Oxo-bicyclo[3.2.1]oct-6-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (51 mg) was taken in THF (3 ml) at 0° C. CH3MgBr (1 ml, 3.0 M) was added and stirred for 2 hrs. The reaction was quenched with sat. NH4Cl, and extracted with ethyl acetate. The organic layer was washed with water, brine, and dried over Na2SO4. Concentration followed by purification on silica column gave the desired product. Mass (ES+ 375).

Provenance & Evidence