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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395959Generated: October 30, 2026

N-bromobutanimide → 5-Bromo-3-(4-pyridyl)-2-(3-trifluoromethylphenyl)indole

https://huagongshe.com/reaction/395959

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
Reactant3-(4-Pyridyl)-2-(3-trifluoromethylphenyl)indoleHCID 18175190—
ReactantHCID 18175227HCID 18175227—
Product5-Bromo-3-(4-pyridyl)-2-(3-trifluoromethylphenyl)indoleHCID 18175250—

Reaction Steps

3-(4-Pyridyl)-2-(3-trifluoromethylphenyl)indole was treated with NBS in the same manner as 6-amino-5-bromo-3-(4-pyridyl)-2-(4-fluorophenyl)-7-aza-indole to afford the title compound: Mass Spectrum (CI) 417 (MBr81-H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605634B2
Source datasetuspto-grants-2003_08
ORD IDord-b67ef57327b54cb49947d4ef4b4ba80c
Source noteuspto-grants-2003_08