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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396030Generated: October 30, 2026

Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 10280341, compound

https://huagongshe.com/reaction/396030

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilaneHCID 12045564—
ReactantHCID 18173501HCID 18173501—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 10280341HCID 102803414,066.7%

Reaction Steps

4-[4-(2-Aminoethyl)phenoxy]-N-(4-fluorobenzyl)-1-piperidinecarboxamide (0.56 g, 1.5 mmol), was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.606 g, 1.5 mmol) according to Procedure G (eluant: 50:1 going to 20:1 dichloromethane-methanol) to give the title compound (0.47 g, Q.61 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605618B2
Source datasetuspto-grants-2003_08
ORD IDord-8741b30f145f4cefae7ac24e23444fea
Source noteuspto-grants-2003_08