HCID 23003068, compound → HCID 23003064, compound

Participants

Reaction Steps

A suspension of 1.570 g (3.116 mmol) of 1-tert-butoxycarbonyl-5-(2,6-dimethyl-4-nitrophenoxy)-3-pentylindazole (Example XXII) and 250 mg (2.349 mmol) of palladium/carbon (10%) in 25 ml of ethanol are hydrogenated under a hydrogen atmosphere for 2 h. The reaction mixture is filtered off through kieselguhr, and the filtrate is concentrated in vacuo and dried. 1.385 g (95% or theory) of 1-tert-butoxycarbonyl-5-(4-amino-2,6-dimethylphenoxy)-3-pentyl-1H-indazole are obtained.

Provenance & Evidence