Dimethylformamide → HCID 9902771, compound

Participants

Reaction Steps

Under Ar, a solution of 3-amino-6-chloro-2-hydroxybenzenesulfonamide (100 mg, 0.45 mmol) and 5-(azidocarbonyl)-1-methylpyrazol (280 mg, 1.85 mmol) in 2 mL of N,N-dimethyl-formamide was stirred at room temperature for 3 days. Purification upon Gilson HPLC, eluting with acetonitrile/water (10/90, v/v to 90/10, v/v, over 10 min), gave the desired product (12 mg, 7.7%). LC-MS (m/z) 346.0 (M+).

Provenance & Evidence