HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Acetoxy-3,5-dimethoxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Acetyl syringic acid | HCID 225680 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 4-Acetoxy-3,5-dimethoxybenzoyl chloride | HCID 97307 | 102.5% |
Reaction Steps
4-Acetoxy-3,5-dimethoxy-benzoic acid (1.45 g) was heated with thionyl chloride (0.86 g) in 3 mL of dimethoxyethane. After 1.5 hours the mixture was stripped under vacuum leaving 1.60 g of 4-acetoxy-3,5-dimethoxy-benzoyl chloride as an oil. 1H NMR (CDCl3, 300 MHz) δ (ppm): 2.26 (s, 3H), 3.89 (s, 9H), 7.34 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524948B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ad47d8dcf06e46af9d5c8f3ec10db8fb |
| Source note | uspto-grants-2013_09 |