p-Bromochlorobenzene → HCID 9950186, compound

HRID 396427Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11](=[O:19])[C:12]1[CH:17]=[CH:16][CH:15]=[C:14](C)[CH:13]=1)=[C:5]2[CH2:20][C:21]([OH:23])=[O:22].BrC1C=CC([Cl:31])=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11](=[O:19])[C:12]1[CH:17]=[CH:16][C:15]([Cl:31])=[CH:14][CH:13]=1)=[C:5]2[CH2:20][C:21]([OH:23])=[O:22]

Participants

Reactant 2

HCID 7806p-Bromochlorobenzene

HCID 9927410HCID 9927410, compound

Product 1

HCID 9950186HCID 9950186, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 7 from 5-chloro-2-[(N-methoxy-N-methylamino)carbonyl]indole (Example 18, step 1) and 4-bromochlorobenzene.

Sources & evidence

ORD record: ord-53e452a9b3754054bcd7d0bd0854c267
Source dataset: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06608070B1

Reaction notes

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