2-Acetyl-4-isopropylpyridine → 2-Bromoacetyl-4-isopropylpyridine

HRID 396458Notes

Reaction equation

HRID 396458 reaction equation
[C:1]([C:4]1[CH:9]=[C:8]([CH:10]([CH3:12])[CH3:11])[CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[Br:13]CC(C1C=C(CC)C=CN=1)=O>>[Br:13][CH2:2][C:1]([C:4]1[CH:9]=[C:8]([CH:10]([CH3:12])[CH3:11])[CH:7]=[CH:6][N:5]=1)=[O:3]

Participants

3

Reactant 2

HCID 5293452-Acetyl-4-isopropylpyridineHCID 230032632-Bromoacetyl-4-ethylpyridine

Product 1

HCID 230032652-Bromoacetyl-4-isopropylpyridine

Procedure

* 2-Bromoacetyl-4-isopropylpyridine was prepared from 2-acetyl-4-isopropylpyridine (K. Ishihama et al., J. Agric. Food Chem., 1992, 40, 1647) according to the procedure for preparing 2-bromoacetyl-4-ethylpyridine described in Example 57.

Sources & evidence

ORD record
ord-67ed1ca242f64b06a7efe83aecf11142
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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