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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396464Generated: October 26, 2026

Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[2-(4-tert-butylpyridine-2-carbonyl)-6-chloro-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396464

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
Reactant2-Bromoacetyl-4-tert-butylpyridineHCID 23003236—
ProductMethyl[2-(4-tert-butylpyridine-2-carbonyl)-6-chloro-1h-indol-3-yl]acetateHCID 23003534—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(penylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-4-tert-butylpyridine*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-4f7fbdac492c42a098a4846ae041d797
Source noteuspto-grants-2003_08