1-(4-tert-Butylpyridin-2-yl)ethan-1-one → 2-Bromoacetyl-4-tert-butylpyridine

HRID 396465Notes

Reaction equation

HRID 396465 reaction equation
[C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[Br:14]CC(C1C=C(CC)C=CN=1)=O>>[Br:14][CH2:2][C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[CH:6][N:5]=1)=[O:3]

Participants

3

Reactant 2

HCID 149959301-(4-tert-Butylpyridin-2-yl)ethan-1-oneHCID 230032632-Bromoacetyl-4-ethylpyridine

Product 1

HCID 230032362-Bromoacetyl-4-tert-butylpyridine

Procedure

* 2-Bromoacetyl-4-tert-butylpyridine was prepared from 2-acetyl-4-tert-butylpyridine (E. C. Constable et al., J. Am. Chem. Soc., 1997, 119, 5606) according to the procedure for preparing 2-bromoacetyl-4-ethylpyridine described in Example 57.

Sources & evidence

ORD record
ord-fbd16225c1674425a3ae1c7b481b527e
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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