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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396467Generated: October 26, 2026

Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[6-chloro-2-(3-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
Reactant2-Bromoacetyl-3-methylpyridine hydrobromideHCID 23003209—
ProductMethyl[6-chloro-2-(3-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003343—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(penylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-3-methylpyridine hydrobromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-32d578719d0e43d19c0219c03462efaa
Source noteuspto-grants-2003_08