1-(3-Methylpyridin-2-yl)ethan-1-one → 2-Bromoacetyl-3-methylpyridine hydrobromide

HRID 396468Notes

Reaction equation

HRID 396468 reaction equation
[C:1]([C:4]1[C:9]([CH3:10])=[CH:8][CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[BrH:11].[Br:12]CC(C1C=C(C)C=CN=1)=O>>[BrH:12].[Br:11][CH2:2][C:1]([C:4]1[C:9]([CH3:10])=[CH:8][CH:7]=[CH:6][N:5]=1)=[O:3]

Participants

3

Reactant 2

HCID 130686691-(3-Methylpyridin-2-yl)ethan-1-oneHCID 230036032-Bromoacetyl4-methylpyridine hydrobromide

Product 1

HCID 230032092-Bromoacetyl-3-methylpyridine hydrobromide

Procedure

* 2-Bromoacetyl-3-methylpyridine hydrobromide was prepared from 2-acetyl-3-methylpyridine (T. A. Crabb et al., Org. Magn. Reson., 1982, 20, 242) according to the procedure for preparing 2-bromoacetyl-4-methylpyridine hydrobromide described in step 2 of Example 31.

Sources & evidence

ORD record
ord-65a6bf89365d4b18af5a8565a69ee50e
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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