HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[6-chloro-2-(6-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate | HCID 11371593 | — |
| Reactant | 2-Bromo-1-(6-methylpyridin-2-yl)ethanone hydrobromide | HCID 22291417 | — |
| Product | Methyl[6-chloro-2-(6-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate | HCID 23003211 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-6-methylpyridine hydrobromide (H. Erlenmeyer, J. Jenni, and B. Prijs, J. Med. Pharm. Chem., 1961, 3, 561-566).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06608070B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-2a92a193e49d4610a18609928def1db7 |
| Source note | uspto-grants-2003_08 |