2-Chloro-5-(trifluoromethyl)pyridine → 2-Bromo-1-[5-(trifluoromethyl)pyridin-2-yl]ethan-1-one

HRID 396472Notes

Reaction equation

HRID 396472 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][N:3]=1.[Br:12][CH2:13][C:14](C1C=CC(C)=CN=1)=[O:15]>>[Br:12][CH2:13][C:14]([C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][N:3]=1)=[O:15]

Participants

3

Reactant 2

HCID 923422-Chloro-5-(trifluoromethyl)pyridineHCID 178014772-Bromo-1-(5-methyl-2-pyridyl)ethanone

Product 1

HCID 230032692-Bromo-1-[5-(trifluoromethyl)pyridin-2-yl]ethan-1-one

Procedure

* 2-Bromoacetyl-5-(trifluoromethyl)pyridine was prepared from 2-chloro-5-(trifluoromethyl)pyridine according to the procedure for preparing 2-bromoacetyl-5-methylpyridine described in step 1 of Example 32.

Sources & evidence

ORD record
ord-6f35bd519eb2484eab701afef9d77021
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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