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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396475Generated: October 26, 2026

2-Bromo-1-(5-chloropyridin-2-yl)ethanone → Methyl[6-chloro-2-(5-chloropyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-(5-chloropyridin-2-yl)ethanoneHCID 11183925—
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
ProductMethyl[6-chloro-2-(5-chloropyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003283—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-5-chloropyridine (Preparation is described in Example 85).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-7ae7571d27524b0680dcdb8afaa502ca
Source noteuspto-grants-2003_08