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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396477Generated: October 29, 2026

3-(2-Bromoacetyl)pyridine hydrobromide → Methyl[6-chloro-2-(pyridine-3-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Bromoacetyl)pyridine hydrobromideHCID 2776234—
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
ProductMethyl[6-chloro-2-(pyridine-3-carbonyl)-1h-indol-3-yl]acetateHCID 23003493—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 3-bromoacetylpyridine hydrobromide (G. B. Barlin, L. P. Davies, S. J. Ireland, M. M. L. Ngu, Aust. J. Chem., 1989, 42, 1735).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-a9ba632693d7432ab68084904e4a120d
Source noteuspto-grants-2003_08