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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396482Generated: October 29, 2026

Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[5-chloro-2-(3,4-dimethylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396482

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 11187263—
Reactant2-Bromoacetyl-3,4-dimethylpyridine hydrobromideHCID 23003478—
ProductMethyl[5-chloro-2-(3,4-dimethylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003515—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetyl-3,4-dimethylpyridine hydrobromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-3e635350ce3e4dd0b7d48696c006b0c9
Source noteuspto-grants-2003_08