1-(4-Methoxy-pyridin-2-yl)-ethanone → 2-Bromoacetyl-4-methoxypyridine hydrobromide

HRID 396487Notes

Reaction equation

HRID 396487 reaction equation
[C:1]([C:4]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][N:5]=1)(=[O:3])[CH3:2].[BrH:12].[Br:13]CC(C1C=C(C)C=CN=1)=O>>[BrH:13].[Br:12][CH2:2][C:1]([C:4]1[CH:9]=[C:8]([O:10][CH3:11])[CH:7]=[CH:6][N:5]=1)=[O:3]

Participants

3

Reactant 2

HCID 218168161-(4-Methoxy-pyridin-2-yl)-ethanoneHCID 230036032-Bromoacetyl4-methylpyridine hydrobromide

Product 1

HCID 230033052-Bromoacetyl-4-methoxypyridine hydrobromide

Procedure

* 2-Bromoacetyl-4-methoxypyridine hydrobromide was prepared from 2-acetyl-4-methoxypyridine (B. Case et al., J. Org. Chem., 1961, 26, 4415) according to the procedure for preparing 2-bromoacetyl-4-methylpyridine hydrobromide described in step 2 of Example 31.

Sources & evidence

ORD record
ord-c4cdce21357447489e35c7ab2261bf0b
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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