Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003410, compound

HRID 396496Notes

Reaction equation

HRID 396496 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.Br.Br[CH2:26][C:27]([C:29]1[C:34]([Cl:35])=[C:33]([CH2:36][CH3:37])[CH:32]=[CH:31][N:30]=1)=[O:28]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:26]=1[C:27]([C:29]1[C:34]([Cl:35])=[C:33]([CH2:36][CH3:37])[CH:32]=[CH:31][N:30]=1)=[O:28]

Participants

3

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(penylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-3-chloro-4-ethylpyridine hydrobromide*.

Sources & evidence

ORD record
ord-d4a13111fa49437e93c8eab8c2463064
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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