Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003334, compound

HRID 396499Notes

Reaction equation

HRID 396499 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14]S(C2C=CC=CC=2)(=O)=O)=[C:6]([CH:13]=1)/[CH:7]=[CH:8]/[C:9]([O:11][CH3:12])=[O:10].Br.Br[CH2:26][C:27]([C:29]1[C:34]([Cl:35])=[C:33]([CH2:36][CH3:37])[CH:32]=[CH:31][N:30]=1)=[O:28]>>[CH3:12][O:11][C:9](=[O:10])[CH2:8][C:7]1[C:6]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:13]=2)[NH:14][C:26]=1[C:27]([C:29]1[C:34]([Cl:35])=[C:33]([CH2:36][CH3:37])[CH:32]=[CH:31][N:30]=1)=[O:28]

Participants

3

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(penylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetyl-3-chloro-4-ethylpyridine hydrobromide (Preparation is described in Example 115).

Sources & evidence

ORD record
ord-d9dcfe6fb8ca43e7aded8dfbb5d501c5
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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