2-Bromoacetyl-4-ethylpyridine → 2-Bromoacetyl-3,4-dimethylpyridine

HRID 396501Notes

Reaction equation

HRID 396501 reaction equation
[C:1](C1C=C(C)C=C(C)N=1)(=O)C.[Br:12][CH2:13][C:14]([C:16]1[CH:21]=[C:20]([CH2:22]C)[CH:19]=[CH:18][N:17]=1)=[O:15]>>[Br:12][CH2:13][C:14]([C:16]1[C:21]([CH3:1])=[C:20]([CH3:22])[CH:19]=[CH:18][N:17]=1)=[O:15]

Participants

3

Reactant 2

HCID 230032632-Bromoacetyl-4-ethylpyridineHCID 230035131-(4,6-Dimethylpyridin-2-yl)ethanone

Product 1

HCID 230034792-Bromoacetyl-3,4-dimethylpyridine

Procedure

* 2-Bromoacetyl-3,4-dimethylpyridine was prepared from 2-acetyl-4,6-dimethylpyridine (Sundberg et al., J. Am. Chem. Soc., 1969, 91, 658) according to the procedure for preparing 2-bromoacetyl-4-ethylpyridine described in Example 57.

Sources & evidence

ORD record
ord-6bfbcb6f14eb49febb3c06e875f69f10
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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