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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396505Generated: October 26, 2026

[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic Acid → Methyl[6-ethyl-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396505

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic AcidHCID 9862267—
ReactantMethyl trans-4-ethyl-2-(p-toluenesulfonylamino)cinnamateHCID 23003522—
ProductMethyl[6-ethyl-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003302—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-ethyl-2-(p-toluenesulfonylamino)cinnamate (step 5) and 2-bromoacetyl-4-methylpyridine hydrobromide (Preparation is described in step 2 of Example 31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-f3796cdbbf304e7ba0f2287bc719e4b9
Source noteuspto-grants-2003_08