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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396517Generated: October 26, 2026

2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-one → Methyl[6-chloro-2-(4-trifluoromethoxybenzoyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396517

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-1-[4-(trifluoromethoxy)phenyl]ethan-1-oneHCID 2778691—
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
ProductMethyl[6-chloro-2-(4-trifluoromethoxybenzoyl)-1h-indol-3-yl]acetateHCID 23003215—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans 4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 4-(trifluoromethoxy)phenacyl bromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-8a812b5f95d04016adc3a448cdeeaf75
Source noteuspto-grants-2003_08