Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003541, compound
Reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.[Cl:24][C:25]1[CH:34]=[CH:33][C:28]([C:29](=[O:32])[CH2:30]Br)=[CH:27][C:26]=1[F:35]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:30]=1[C:29](=[O:32])[C:28]1[CH:33]=[CH:34][C:25]([Cl:24])=[C:26]([F:35])[CH:27]=1Participants
3
Procedure
The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 4-chloro-3-fluorophenacyl bromide* .
Sources & evidence
- ORD record
- ord-3f945b5923eb48cf9053d99536ee898b
- Source dataset
- uspto-grants-2003_08
- Patent number
- US06608070B1
Reaction notes
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