4-(Bromoacetyl)benzonitrile → HCID 23003217, compound

HRID 396524Notes

Reaction equation

HRID 396524 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.[C:24]([C:26]1[CH:35]=[CH:34][C:29]([C:30](=[O:33])[CH2:31]Br)=[CH:28][CH:27]=1)#[N:25]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:31]=1[C:30](=[O:33])[C:29]1[CH:34]=[CH:35][C:26]([C:24]#[N:25])=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 986544-(Bromoacetyl)benzonitrileHCID 11371593Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate

Product 1

HCID 23003217HCID 23003217, compound

Procedure

The title compound was prepared according to the procedure described in Example 8 (Method B) from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 4-cyanophenacyl bromide.

Sources & evidence

ORD record
ord-7bdd1b2f770847678ee0c2cc8e6a8aad
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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