Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003482, compound

HRID 396532Notes

Reaction equation

HRID 396532 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.Br.Br[CH2:26][C:27]([C:29]1[N:30]=[CH:31][C:32]2[C:37]([CH:38]=1)=[CH:36][CH:35]=[CH:34][CH:33]=2)=[O:28]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:26]=1[C:27]([C:29]1[N:30]=[CH:31][C:32]2[C:37]([CH:38]=1)=[CH:36][CH:35]=[CH:34][CH:33]=2)=[O:28]

Participants

3

Reactant 2

HCID 11371593Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 23003351231297-28-2

Product 1

HCID 23003482HCID 23003482, compound

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 3-bromoacetylisoquinoline (Preparation is described in Example 220).

Sources & evidence

ORD record
ord-fc2c974879ee440fa2617b78abf0a1c6
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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