Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003245, compound

HRID 396542Notes

Reaction equation

HRID 396542 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.Br[CH2:25][C:26]([C:28]1[S:29][C:30]([CH3:33])=[CH:31][N:32]=1)=[O:27]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:25]=1[C:26]([C:28]1[S:29][C:30]([CH3:33])=[CH:31][N:32]=1)=[O:27]

Participants

3

Reactant 2

HCID 11371593Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 23003251HCID 23003251, compound

Product 1

HCID 23003245HCID 23003245, compound

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 2-bromoacetyl-5-methylthiazole (Preparation is described in Example 232).

Sources & evidence

ORD record
ord-909a6b6034db4dabb6119a89e4711bde
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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