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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396544Generated: October 26, 2026

2-Bromoacetyl-1-methylimidazole hydrobromide → [6-Chloro-2-(1-methylimidazole-2-carbonyl)-1H-indol-3-yl]acetic Acid

https://huagongshe.com/reaction/396544

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoacetyl-1-methylimidazole hydrobromideHCID 22049840—
ReactantMethyl trans-4-chloro-2-(ethoxycarbonylamino)cinnamateHCID 23003310—
Product[6-Chloro-2-(1-methylimidazole-2-carbonyl)-1H-indol-3-yl]acetic AcidHCID 18542187—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 31 from methyl trans-4-chloro-2-(ethoxycarbonylamino)cinnamate (Example 31, step 1) and 2-bromoacetyl-1-methylimidazole hydrobromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-32eaa891b36a4408a9dcf2efdf9b5863
Source noteuspto-grants-2003_08