Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → HCID 23003453, compound

HRID 396548Notes

Reaction equation

HRID 396548 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14]S(C2C=CC=CC=2)(=O)=O)=[C:6]([CH:13]=1)/[CH:7]=[CH:8]/[C:9]([O:11][CH3:12])=[O:10].Cl[CH2:25][C:26]([C:28]1[N:29](COCC[Si](C)(C)C)[CH:30]=[CH:31][N:32]=1)=[O:27]>>[CH3:12][O:11][C:9](=[O:10])[CH2:8][C:7]1[C:6]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:13]=2)[NH:14][C:25]=1[C:26]([C:28]1[NH:29][CH:30]=[CH:31][N:32]=1)=[O:27]

Participants

3

Reactant 2

HCID 11187263Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 23003605HCID 23003605, compound

Product 1

HCID 23003453HCID 23003453, compound

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 2-chloroacetyl-l-[2-(trimethylsilyl)ethoxymethyl]imidazole.*

Sources & evidence

ORD record
ord-5bfa090873a14b4f89452d001f83daa6
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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