Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → HCID 9905056, compound

HRID 396550Notes

Reaction equation

HRID 396550 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH3:11])=[O:9])=[C:4]([NH:14]S(C2C=CC=CC=2)(=O)=O)[CH:3]=1.COC(=O)CC1C2C(=CC=C(Cl)C=2)N[C:29]=1[C:38]([C:40]1[NH:41][CH:42]=[CH:43][N:44]=1)=[O:39]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][C:6]1[C:5]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:13][CH:12]=2)[NH:14][C:29]=1[C:38]([C:40]1[NH:41][CH:42]=[CH:43][N:44]=1)=[O:39]

Participants

3

Reactant 2

HCID 11371593Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 23003453HCID 23003453, compound

Product 1

HCID 9905056HCID 9905056, compound

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (Step 1 of Example 8, Method A) and 2-chloroacetyl-1-[2-(trimethylsilyl)ethoxymethyl]imidazole (Preparation is described in step 1 of Example 245).

Sources & evidence

ORD record
ord-63bc811e5b97457c8f89102f706e3489
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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