2-Chloro-1-(1-methyl-1H-pyrrol-2-yl)-ethanone → HCID 23003285, compound

HRID 396552Notes

Reaction equation

HRID 396552 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14]S(C2C=CC=CC=2)(=O)=O)=[C:6]([CH:13]=1)/[CH:7]=[CH:8]/[C:9]([O:11][CH3:12])=[O:10].Cl[CH2:25][C:26]([C:28]1[N:29]([CH3:33])[CH:30]=[CH:31][CH:32]=1)=[O:27]>>[CH3:12][O:11][C:9](=[O:10])[CH2:8][C:7]1[C:6]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:13]=2)[NH:14][C:25]=1[C:26]([C:28]1[N:29]([CH3:33])[CH:30]=[CH:31][CH:32]=1)=[O:27]

Participants

3

Reactant 2

HCID 25124042-Chloro-1-(1-methyl-1H-pyrrol-2-yl)-ethanoneHCID 11187263Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate

Product 1

HCID 23003285HCID 23003285, compound

Procedure

The title compound was prepared according to the procedure described in Example 8 (Method B) from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 2-chloroacetyl-1-methylpyrrole (P. D. Croce et al., Synthesis, 1990, 212).

Sources & evidence

ORD record
ord-1f59f3a285f64a4b8030dc8888133228
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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