Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → HCID 178499528, compound

HRID 396554Notes

Reaction equation

HRID 396554 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([NH:14]S(C2C=CC=CC=2)(=O)=O)=[C:6]([CH:13]=1)/[CH:7]=[CH:8]/[C:9]([O:11][CH3:12])=[O:10].Br[CH2:25][C:26]([C:28]1[N:29]=[C:30]([CH3:33])[NH:31][CH:32]=1)=[O:27]>>[CH3:12][O:11][C:9](=[O:10])[CH2:8][C:7]1[C:6]2[C:5](=[CH:4][CH:3]=[C:2]([Cl:1])[CH:13]=2)[NH:14][C:25]=1[C:26]([C:28]1[N:29]=[C:30]([CH3:33])[NH:31][CH:32]=1)=[O:27]

Participants

3

Reactant 2

HCID 11187263Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 178432971HCID 178432971, compound

Product 1

HCID 178499528HCID 178499528, compound

Procedure

The title compound was prepared according to the procedure described in Example 8 (Method B) from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 4-bromoacetyl-2-methylimidazole (Deady, Leslie W. et al., Aust. J. Chem., 1981, 34, 1295).

Sources & evidence

ORD record
ord-6fd0939dcb7347da9aead3fafc1c1749
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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