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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396555Generated: October 29, 2026

Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[5-chloro-2-(thiazole-5-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396555

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 11187263—
Reactant2-Bromo-1-(thiazol-5-yl)ethanone hydrobromideHCID 23003558—
ProductMethyl[5-chloro-2-(thiazole-5-carbonyl)-1h-indol-3-yl]acetateHCID 23003501—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 5-bromoacetylthiazole hydrobromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-933728d1be43424095a1fd9f9c8d3d05
Source noteuspto-grants-2003_08