2-Acetyl-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridine → 2-Bromoacety-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridine

HRID 396569Notes

Reaction equation

HRID 396569 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[C:9]([CH2:11][O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:15])[CH3:14])[CH:8]=[CH:7][N:6]=1)=[O:4].[C:20](C1C=C(C(O[Si](C(C)(C)C)(C)C)C)C=CN=1)(=O)C>>[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[C:9]([CH:11]([O:12][Si:13]([C:16]([CH3:19])([CH3:18])[CH3:17])([CH3:14])[CH3:15])[CH3:20])[CH:8]=[CH:7][N:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 230033192-Acetyl-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridineHCID 230035802-Bromoacetyl-4-(tert-butyldimethylsilyloxymethyl)pyridine

Product 1

HCID 230034202-Bromoacety-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridine

Procedure

The title compound was prepared according to the procedure for preparing 2-bromoacetyl-4-(tert-butyldimethylsilyloxymethyl)pyridine described in Example 95 from 2-acetyl-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridine.

Sources & evidence

ORD record
ord-67dfd99d90654d4fbf544907ba96f2ca
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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