[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic Acid → HCID 9884363, compound

HRID 396571Notes

Reaction equation

HRID 396571 reaction equation
C1(C)C=C[C:4]([S:7](NC2C=CC(C)=CC=2/C=C/C(OC)=S)(=O)=O)=CC=1.Cl[C:26]1[CH:34]=[C:33]2[C:29]([C:30]([CH2:44][C:45]([OH:47])=[O:46])=[C:31]([C:35]([C:37]3[CH:42]=[C:41]([CH3:43])[CH:40]=[CH:39][N:38]=3)=[O:36])[NH:32]2)=[CH:28][CH:27]=1>>[CH3:43][C:41]1[CH:40]=[CH:39][N:38]=[C:37]([C:35]([C:31]2[NH:32][C:33]3[C:29]([C:30]=2[CH2:44][C:45]([OH:47])=[O:46])=[CH:28][C:27]([S:7][CH3:4])=[CH:26][CH:34]=3)=[O:36])[CH:42]=1

Participants

3

Reactant 2

HCID 9862267[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic AcidHCID 86759116HCID 86759116, compound

Product 1

HCID 9884363HCID 9884363, compound

Procedure

The title compound was prepared according to the procedure described in Example 57 from methyl trans-2-p-toluenesulfonylamino-5-methylthiocinnamate (step 2) and 2-bromoacetyl-4-methylpyridine hydrobromide (Preparation is described in step 2 of Example 31).

Sources & evidence

ORD record
ord-3ec88defebe14d8d8eec012d5a017a56
Source dataset
uspto-grants-2003_08
Patent number
US06608070B1

Reaction notes

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