反应详情

To 20 mL of an ethanol solution containing 2.0 g of 1-tert-butyl 4-ethyl 4-(3-(benzyloxy)propyl)piperidine-1,4-dicarboxylate, 2 mL of an ethanol suspension containing 0.30 g of 10% palladium carbon was added, and the mixture was stirred for 4 hours under a hydrogen atmosphere. The insoluble material filtered off, and the solvent was removed under reducer pressure to obtain 1.7 g of a colorless oily substance, 1-tert-butyl 4-ethyl 4-(3-hydroxypropyl)piperidine-1,4-dicarboxylate.

1. additionwas added
2. filtrationThe insoluble material filtered off
3. customthe solvent was removed under reducer pressure