Furan-2-boronic acid → HCID 22316925, compound

HRID 396771Notes

Reaction equation

HRID 396771 reaction equation
[O:1]1C=C[CH:3]=[C:2]1B(O)O.[Br:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[N:20]([C:21]3[CH:26]=[CH:25][C:24]([S:27]([CH3:30])(=[O:29])=[O:28])=[CH:23][CH:22]=3)[N:19]=[C:18]([CH2:31][OH:32])[CH:17]=2)=[CH:12][CH:11]=1>>[Br:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[N:20]([C:21]3[CH:26]=[CH:25][C:24]([S:27]([CH3:30])(=[O:29])=[O:28])=[CH:23][CH:22]=3)[N:19]=[C:18]([C:31]([O:1][CH2:2][CH3:3])=[O:32])[CH:17]=2)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 2734357Furan-2-boronic acidHCID 86584958HCID 86584958, compound

Product 1

HCID 22316925HCID 22316925, compound

Procedure

The title compound was prepared according to the procedure of Example 1 using 2-furanboronic acid instead of 2-thiophenboronic acid acid and 4-[5-[4-Bromophenyl]-3-hydroxymethy-1-[4-(methylsulfonyl)phenyl]-1H-pyrazole instead of 1-[4-(Methylsulfonyl)phenyl]-5-(4-bromophenyl)-3-trifluoromethyl-1H-pyrazole in step 2.

Sources & evidence

ORD record
ord-d99354d19fc74fb0acfe299956254529
Source dataset
uspto-grants-2003_08
Patent number
US06608095B2

Reaction notes

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