Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396803Generated: October 29, 2026

3-Fluoro-4-sulfamoylphenylhydrazine hydrochloride → 4-[5-[3-Chloro-4-(2-furyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-fluorobenzenesulfonamide

https://huagongshe.com/reaction/396803

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-sulfamoylphenylhydrazine hydrochlorideHCID 22316669—
Reactant1-[3-Chloro-4-(2-furyl)phenyl]-4,4,4-trifluoro-1,3-butanedioneHCID 22316700—
Product4-[5-[3-Chloro-4-(2-furyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-fluorobenzenesulfonamideHCID 22316710—

Reaction Steps

The title compound was prepared according to the procedure of Example 60 using 3-fluoro-4-sulfamoylphenylhydrazine hydrochloride instead of 3-fluoro-4-(methylsulfonyl)phenylhydrazine hydrochloride and 4,4,4-trifluoro-1-[3-chloro-4-(2-furyl)phenyl]butane-1,3-dione instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione in step 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608095B2
Source datasetuspto-grants-2003_08
ORD IDord-8787fc71def04d49a38d528f99927cf9
Source noteuspto-grants-2003_08