Furan-2-boronic acid → HCID 22316726, compound

HRID 396816Notes

Reaction equation

HRID 396816 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[C:15]([F:23])[CH:14]=3)[N:11]=[CH:10][C:9]=2[C:24]#[N:25])=[CH:4][CH:3]=1.[O:26]1[CH:30]=[CH:29][CH:28]=[C:27]1B(O)O>>[C:24]([C:9]1[CH:10]=[N:11][N:12]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[C:15]([F:23])[CH:14]=2)[C:8]=1[C:5]1[CH:6]=[CH:7][C:2]([C:27]2[O:26][CH:30]=[CH:29][CH:28]=2)=[CH:3][CH:4]=1)#[N:25]

Participants

3

Reactant 2

HCID 2734357Furan-2-boronic acidHCID 22316638HCID 22316638, compound

Product 1

HCID 22316726HCID 22316726, compound

Procedure

The title compound was prepared according to the procedure of Example 5 using 5-(4-bromophenyl)-4-cyano-1-[3-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazole instead of 4-[5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-1-phenylsulfonamide, 2-furanboronic acid instead of 3-thienylboronic acid.

Sources & evidence

ORD record
ord-a936b8ab0e3e4c2b8180d23ef550212e
Source dataset
uspto-grants-2003_08
Patent number
US06608095B2

Reaction notes

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